A eficácia da suplementação de vitamina D em portadores de asma: metanálise de ensaios clínicos

Resumo

The objective of this systematic review and meta-analysis was to evaluate the efficacy of vitamin D supplementation for asthma. Data Sources: PubMed, Web of Science, Scopus and Science Direct through July 2017. The results showed that there was a reduced risk of asthma exacerbations in subject receiving vitamin D (RR 0.70, 95% CI: 0,55 to 0,91).There was significant effect lung function (WMD:1,65; 95% CI:0,14 to 3,17). The serum 25(OH)D level was higher in the vitamin D group at the end of the intervention (WMD: 22,14 nmol; 95% CI:11,42 to 32,85). In conclusion, vitamin D supplementation as a potential target to aid in asthma management