Eficácia da suplementação de vitamina D em indivíduos com obesidade: metanálise de ensaios clínicos

Resumo

The objective of this systematic review and meta-analysis was to assess the effects of vitamin D supplementation for obese. Data Sources: PubMed, Web of Science, Scopus and Science Direct databases. The results of the meta-analysis showed that there was a significant treatment effect of vitamin D supplementation on vitamin D serum concentration of obese (35.12 nmol/L; 95% CI = 28-42.20) . However, obesity decreases the response to vitamin D supplementation (30.22 nmol/L; 95 CI = 28-42.20) bese subjects compared to the eutrophic group. In conclusion, vitamin D supplementation was significantly lower in the obese.