Avaliação da atividade mnemônica de Amburana cearensis (Allemão) A. C. Sm


  • Jéssica M.G.S.R. Almeida
  • Pablinny M.G. Carvalho
  • Katyuscya V. Leão
  • Elson A. Costa
  • Marina M. Paes


The anticholinesterases are the principal drugs used to treat memory impairment in neurodegenerative disorders. Amburana cearensis (Allema) A. C. Sm. (Fabaceae) is popularly used in the treatment of various diseases. The hydroalcoholic extract of A. cearensis stem bark (EHA) has anticholinesterase activity in vitro. This work investigated the mnemonic activity of EHA in the step-down inhibitory avoidance test with mice submitted to acute oral treatment (100, 300 or 1000 mg/kg), without and with scopolamine-induced amnesia. As well as, the EHA effects on anxiety and locomotor behaviors.